A tall and heavy concrete building is always more vulnerable to erthquakes than a light and low wooden building. You can imagine stresses should be greatest on the pillers and walls on the lowest floors.

Also, if 2 or more quake-waves (e.g. reflected waves) arrive in the same area, you could expect constructive and destructive interferences of the waves, resulting in very high quake at one spot and almost no quake at a spot next to it. So, you could see desvastating destruction at one spot and a totally unscathed area next to it.

I hope I've got my physics right above!